There does not exist any underground railroad between Ohio and Florida and thus, the fastest way to get from Ohio to Florida would be by taking an airplane.
Explanation:
The distance between Ohio and Florida is approximately 1350 kilometers or 838 miles.
To reach Florida from Ohio by road would take at least 12 to 13 hours.
As there is no railroad link between Ohio and Florida, the only option other than going by road is going by airplane which takes around 2 to 2.5 hours.