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Why did diseases spread so rapidly in the Americas after European explorers arrived?
The diseases affected the body’s major organs.
The diseases were highly contagious.
The diseases affected the immune system.
The diseases were harmful to the skin.

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Answer:

Diseases spread so quickly in America when European explorers arrived because in America, people didn't have the small pox virus or the plauge.  Whereas in Europe, overtime they became immune to it.  The people in America were isolated and never experienced that before. This caused the Americans to get really sick and even die.

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