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Histamine is a chemical substance released in inflammatory and allergic responses. the histamine h1 receptor is a g protein-coupled receptor that activates phospholipase c in response to the binding of histamine. complete the flowchart showing the process of histamine signal transduction from the h1 receptor. drag the labels to their appropriate locations in the flowchart. some labels will not be used.

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The following labels to their appropriate location in the flowchat;

1. ENZYME CLEAVES PIP
2,FORMING DAG AND IP32. IP3 BINDS TO A LIGANDGATED ION CHANNEL IN THE ER MEMBRANE.
3. CALCIUM IONS FLOW THROUG THE LIGAND-GATED ION CHANNEL.
4. CALCIUM ION CONCENTRATION INCREASES IN THE CYTOSOL.
5. CALCIUM IONS ACTIVATE A PROTEIN, LEADING TO A CELLULAR RESPONSE

That is the answer that will complete your flowchart.

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